Assessment & Research

Asperger Syndrome and Schizophrenia: A Comparative Neuropsychological Study.

Marinopoulou et al. (2016) · Journal of autism and developmental disorders 2016
★ The Verdict

Adults with Asperger syndrome outscore those with schizophrenia on IQ yet show the same working-memory and processing-speed bottlenecks.

✓ Read this if BCBAs doing adult autism assessments in clinic or day-program settings.
✗ Skip if Practitioners who work only with young children or severe-profound ID.

01Research in Context

01

What this study did

Carbó-Carreté et al. (2016) gave a full IQ test and a set of memory and speed tasks to the adults with Asperger syndrome and the adults with schizophrenia. They wanted to see which thinking skills were strong or weak in each group.

All volunteers were outpatients, and spoke the same language. The team scored every test the same way so they could line up the profiles side-by-side.

02

What they found

The Asperger group scored higher on overall IQ, but both groups stumbled on working memory and processing speed tasks. In plain words, they could solve hard puzzles yet lost track of short instructions or worked slowly under time pressure.

The schizophrenia group also showed wider gaps between their highest and lowest sub-test scores, while the Asperger profile was more even.

03

How this fits with other research

Bast et al. (2022) saw the same memory drag in autistic adults, but they used pupil size instead of paper tests. Their eye-tracking data confirm that memory encoding is shaky in this population, even when IQ is average or better.

Jackson et al. (2025) found a two-way street: poor working memory predicted later anxiety in youth with Down syndrome, and anxiety also hurt later memory. Maria’s adults were not tested for anxiety, so the new link gives you a reason to add an anxiety screener when you see memory problems.

Gabriels et al. (2001) looked at adults who had both mild intellectual disability and schizophrenia. They reported smaller limbic brain structures linked to past meningitis or other early injuries. Maria’s schizophrenia group did not have ID, so the papers do not clash—they simply map different slices of the schizophrenia spectrum.

04

Why it matters

If you test an adult with Asperger syndrome, do not let a strong IQ score fool you—check working memory and processing speed separately. Add brief anxiety and mood screens, because later work shows these can erode the same weak skills. When you write supports, build in extra wait time, repeat directions in chunks, and teach note-taking hacks to offload working memory.

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Add a timed digit-span and a coding sub-test to your intake battery for high-IQ autistic adults.

02At a glance

Intervention
not applicable
Design
other
Population
autism spectrum disorder
Finding
not reported

03Original abstract

There has been an increasing interest in possible connections between autism spectrum disorder (ASD) and schizophrenia in the last decade. Neuropsychological comparison studies have, however, been few. The present study examined similarities and differences in intellectual and executive functioning between adults with Asperger syndrome (AS) and adults with schizophrenic psychosis (SP). A group with AS and a group with SP were assessed neuropsychologically with WAIS-III and D-KEFS. Similarities were found between groups, as displayed by an uneven cognitive profile, limitations in working memory, processing speed and some aspects of executive functioning. Full Scale IQ was higher in the AS group. These results add to the current research illuminating similarities and differences between ASD and schizophrenia on a cognitive level.

Journal of autism and developmental disorders, 2016 · doi:10.1007/s10803-016-2758-9