A review of the nature and treatment of sleep disorders in individuals with developmental disabilities.
Sleep problems are the norm, not the exception, across developmental disabilities, and newer studies show you can fix most cases with melatonin plus simple behavioral tweaks before reaching for stricter plans.
01Research in Context
What this study did
Fox et al. (2001) read every paper they could find on sleep in people with developmental disabilities. They grouped the studies by type of sleep problem and type of treatment. The goal was to see how common sleep issues are and what seems to help.
The review covers both children and adults. It looks at autism, intellectual disability, and rarer genetic syndromes. Papers span from the 1980s up to 2001.
What they found
Sleep problems are common, but the exact numbers jump around. One survey says 26 % of adults have trouble falling asleep. Another says 56 % wake up at night. The wide range makes it hard to plan services.
Behavioral plans and melatonin both show promise, yet the evidence is mixed. The authors call for clearer data and better studies.
How this fits with other research
Gaily et al. (1998) is a direct predecessor. That community survey of adults with ID supplies one of the few hard numbers the 2001 review cites. It shows night waking is the top complaint.
Woodford et al. (2024) is a successor. Their single-case study tests the very behavioral packages the 2001 paper said were needed. They find most kids improve with simple circadian cues before any extinction is added.
Sadeh et al. (2023) also updates the story. Where the 2001 review calls melatonin evidence "mixed," the 2023 parent survey shows strong long-term adherence and real-world gains for autistic children.
Lee et al. (2022) ties it all together. Their meta-analysis of 49 studies confirms poor sleep predicts worse daytime mood, behavior, and thinking skills in autism. This quantifies the daytime link the 2001 review could only describe.
Why it matters
If you write sleep protocols, treat this review as your map of old gaps and new answers. Start with low-dose melatonin and light bedtime routines first. Add extinction only if simple steps fail. Track both night data and next-day behavior so you can show parents the daytime payoff.
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02At a glance
03Original abstract
This paper describes research on the prevalence, correlates, and treatment of sleep disorders in individuals with developmental disabilities. A significant number of individuals with developmental disabilities have disordered sleep, although prevalence estimates vary from 13% to 86%. Constitutional variables, including age, presence of physical and sensory impairments, and certain genetic syndromes and medical conditions appear to be related to sleep disturbance, but the evidence is mainly correlational and therefore cannot be said to show a causal relation. While a number of behavioral interventions have proven effective in the treatment of sleep disturbance, and drug therapy involving melatonin appears promising, epidemiologic work on the correlates of sleep disorders appear to have had little impact on treatment. Consideration of the nature of sleep disorders may enhance treatments for individuals with developmental disabilities.
Research in developmental disabilities, 2001 · doi:10.1016/s0891-4222(01)00071-3