Assessment & Research

A follow-up study of early onset psychosis: comparison between outcome diagnoses of schizophrenia, mood disorders, and personality disorders.

McClellan et al. (1993) · Journal of autism and developmental disorders 1993
★ The Verdict

Early psychosis labels often change, yet chronic impairment remains, so focus on behavioral needs, not the first diagnosis.

✓ Read this if BCBAs working with adolescents who carry or are being assessed for early psychosis in school or clinic settings.
✗ Skip if Practitioners serving only preschoolers or clients with stable ID diagnoses and no psychotic features.

01Research in Context

01

What this study did

Castañe et al. (1993) tracked 39 young people who had shown early signs of psychosis. They checked back years later to see what diagnoses stuck and how the kids were doing.

The team compared three outcome groups: schizophrenia, mood disorders, and personality disorders. They used charts, interviews, and school records to paint a picture of long-term functioning.

02

What they found

Labels shifted a lot. Many youths who first looked schizophrenic later carried mood- or personality-disorder tags instead.

No matter the final label, most still struggled with school, work, or friendships. The study paints early psychosis as a moving target with lasting impact.

03

How this fits with other research

Hayes (1989) saw similar label changes but brighter outcomes in kids whose final tag was schizo-affective. The mixed group in Castañe et al. (1993) makes the outlook look grimmer, yet both agree that first labels often change.

Pakenham et al. (2004) extended the idea to youth with intellectual disability. They found careful re-evaluation often drops the psychosis label altogether, backing the 1993 warning that early tags can be shaky.

Herrnstein et al. (1979) looked even younger, at preschoolers. Their tiny patients sometimes improved more than school-age kids in Castañe et al. (1993), hinting that age at first episode may steer the road ahead.

04

Why it matters

For BCBAs, the message is to treat behaviors, not the initial diagnosis. A teen who hears voices today may later be called bipolar or borderline, but skill deficits and reinforcement patterns still need your attention. Keep data, expect change, and avoid locking a learner into a schizophrenia box that may not last.

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Review each learner’s current goals; if they rest on a shaky schizophrenia label, add baseline skill probes that stay useful no matter the future diagnosis.

02At a glance

Intervention
not applicable
Design
case series
Sample size
39
Population
mixed clinical
Finding
not reported

03Original abstract

This study examined the outcome of youth previously diagnosed with psychotic disorders at a public-sector tertiary care hospital. Of 95 children and adolescents retrospectively identified, follow-up information (mean interval 3.9 years) was obtained on 24 subjects with an outcome diagnosis of schizophrenia, 9 with psychotic mood disorders, 5 with personality disorders (antisocial or borderline), and 1 with schizo-affective disorder. The schizophrenic group was more often odd premorbidly and functioned worse at outcome, while the mood-disordered group had a shorter follow-up period and was more often anxious or dysthymic premorbidly. The personality-disordered group resembled the schizophrenics in their degree of impairment and chronicity. All three groups had high rates of family disruption, low SES, substance abuse, and chronicity, and were similar in their degree of premorbid impairment, length of prodrome, age of onset, initial diagnosis, and family psychiatric history. Misdiagnosis at onset was quite common and highlights the need for systematic longitudinal assessment of early onset psychotic disorders.

Journal of autism and developmental disorders, 1993 · doi:10.1007/BF01046218