ABA Fundamentals

Effects of d-amphetamine and chlordiazepoxide on spaced responding in pigeons.

McMillan et al. (1970) · Journal of the experimental analysis of behavior 1970
★ The Verdict

New meds can wipe out DRL timing—expect dips and plan quick fixes.

✓ Read this if BCBAs running DRL or self-control programs with clients on stimulants or anxiety meds.
✗ Skip if Clinicians working only on skill acquisition without timing or medication issues.

01Research in Context

01

What this study did

Researchers gave pigeons a DRL 20-second schedule. The birds had to wait 20 seconds between pecks to earn food.

They then injected low or high doses of two drugs. One drug was a stimulant (d-amphetamine). The other was a calming drug (chlordiazepoxide).

The team watched how the drugs changed the birds' timing and any extra movements the birds made.

02

What they found

Small doses only hurt timing for half the birds. Big doses always made the birds peck too soon or stop pecking.

The birds did not use new side movements to help them wait. The drugs acted right on the timing system.

03

How this fits with other research

Byrd (1972) and Cicerone (1976) used the same DRL task but changed lights instead of drugs. They showed that timing is tightly tied to the stimulus in front of the bird. Hearst et al. (1970) now shows that drugs can break that timing without needing new cues.

Flory et al. (1974) tied the birds’ wings so they could not pace or turn while waiting. This raised response rates and cut rewards. The 1970 drug study found no helpful collateral moves, so both papers warn that blocking or drugging natural pacing can wreck DRL success.

Wilson et al. (1973) gave the same stimulant under mild punishment. There, amphetamine sometimes raised punished pecks. In the 1970 DRL case, the same drug only lowered or stopped spaced pecks. The difference is the contingency: punishment keeps the door open for rate increases, DRL does not.

04

Why it matters

If a client starts new meds, watch their DRL or self-control tasks closely. Even small dose changes can erase hard-won wait times. Have backup plans ready, like shorter DRL values or extra prompts, to keep the skill alive.

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→ Action — try this Monday

Check the last week’s DRL data for any client with a new prescription—drop the DRL value by 5 seconds if response rates spike.

02At a glance

Intervention
not applicable
Design
single case other
Population
other
Finding
mixed
Magnitude
small

03Original abstract

The effects of d-amphetamine and chlordiazepoxide were studied in pigeons on performance (1) under a schedule that reinforced responses on a key (food key) if they were more than 20 sec apart, (2) under the same schedule when responses also were required on a collateral key during the interresponse time on the food key, and (3) under the same schedule when responses were required on a collateral key during the interresponse time on the food key and collateral-key responses could produce a stimulus correlated with the availability of food. Under all three spaced-responding schedules, d-amphetamine and chlordiazepoxide at low dose levels slightly increased the frequency of short interresponse times on the food key for about half the birds, and either did not affect the interresponse time patterns of the other birds, or lengthened the durations slightly. At higher dose levels, d-amphetamine and chlordiazepoxide increased the frequency of long interresponse times or abolished responding in all birds. Changes in the pattern of interresponse times on the food key did not seem to depend on changes in the rate or pattern of collateral-key responses.

Journal of the experimental analysis of behavior, 1970 · doi:10.1901/jeab.1970.14-177