ABA Fundamentals

Drug discrimination: stimulus control during repeated testing in extinction.

Zarcone et al. (2000) · Journal of the experimental analysis of behavior 2000
★ The Verdict

Stimulus control can stay solid while response rate falls—track consecutive corrects, not just totals, during extinction.

✓ Read this if BCBAs running extinction or FCT who need clean measures of stimulus control.
✗ Skip if Practitioners focused solely on acquisition with no extinction phase planned.

01Research in Context

01

What this study did

Rose et al. (2000) tested pigeons in a drug-discrimination task. Birds first learned to peck one key when given a drug and another key when given saline.

After training, the team ran daily extinction sessions. No food was given for correct or wrong pecks. They repeated these drug-free tests many times.

02

What they found

Response rate dropped across extinction days, but stimulus control stayed strong. The birds still chose the drug-appropriate key most of the time.

Counting the percentage of FR10 runs showed clearer control than simple rate. Low peck numbers had hidden the true accuracy until they used the ratio measure.

03

How this fits with other research

Podlesnik et al. (2016) later showed the same logic works with alternative reinforcement. They gave rich food in a separate context before mixing it with the target task. Extinction went faster, proving the 2000 finding extends to reinforcement-rich histories.

Fisher et al. (2020) applied the idea to kids with destructive behavior. Adding an S-delta during FCT extinction cut resurgence. The birds' stable stimulus control under repeated extinction told the team that a clear 'no-reinforcement' signal would hold even when response rate fell.

Shahan et al. (2020) measured resurgence as alternative reinforcement thinned. They also moved past simple rate, modeling relapse size. Their fine-grained tracking echoes the 2000 paper's switch to percentage of FR10s: both warn that raw counts can mislead.

04

Why it matters

When you run extinction, watch how you score stimulus control. If responses drop but accuracy looks shaky, switch to a consecutive-response ratio instead of total count. Add an S-delta card or tone when you probe, just like Fisher did, to keep control tight. And plan for resurgence any time you thin reinforcement—Shahan's curve tells us the relapse jumps fast. One practical step: record ten correct responses in a row before you say the learner 'has it' during extinction probes.

Free CEUs

Want CEUs on This Topic?

The ABA Clubhouse has 60+ free CEUs — live every Wednesday. Ethics, supervision & clinical topics.

Join Free →
→ Action — try this Monday

Tally ten-in-a-row correct responses before ending an extinction probe session.

02At a glance

Intervention
not applicable
Design
single case other
Finding
positive

03Original abstract

Rats were trained, under a two-lever drug-discrimination procedure, to respond differentially depending upon whether lorazepam (1.0 mg/kg) or no injection had been administered before the session. Responses on the appropriate lever produced a food pellet under a modified fixed-ratio (FR) 10 schedule, in which the 10 responses had to be emitted consecutively. In reinforcement tests, completing an FR 10 on either lever produced a pellet. In extinction tests, stimulus changes paired with reinforcement occurred but no pellet was delivered. Training sessions were conducted between test sessions. Each of four extinction phases consisted of six tests preceded by one stimulus (e.g., lorazepam). Repeated exposures to extinction reduced response rates for all rats, but stimulus control, as inferred from either percentage of total responses or percentage of total FR 10s on the drug-appropriate lever, remained high. The percentage of total FR 10s measure was less subject to skewing under low-rate conditions than was the percentage of total responses measure and provided an evaluation of stimulus control in terms of meeting the consecutive response contingency. These results demonstrate a level of independence between response rate and stimulus control in drug discrimination, which has positive implications for the validity of interpreting discriminative effects of novel test conditions in well-trained animals, even when overall response rates are low.

Journal of the experimental analysis of behavior, 2000 · doi:10.1901/jeab.2000.74-283