Autism & Developmental

Intervention for infants at risk of developing autism: a case series.

Green et al. (2013) · Journal of autism and developmental disorders 2013
★ The Verdict

Coaching parents through video when babies are 8–10 months is doable, but we still do not know if it changes the autism pathway.

✓ Read this if BCBAs running early-intervention clinics or sibling-tracking programs.
✗ Skip if Clinicians seeking evidence-based treatments with proven child outcomes.

01Research in Context

01

What this study did

Green et al. (2013) filmed parents playing with their 8- to 10-month-old babies who had an older sibling with autism. The team then coached the parents to spot and respond to tiny social cues.

Each family got a short video lesson and practiced at home. The study only asked, “Can we run this?” It did not test if the babies later got an autism diagnosis.

02

What they found

Parents said the plan was easy and helpful. Staff could collect all planned data, so the method was judged doable.

No child outcome numbers were reported. The paper simply shows the project is possible to run.

03

How this fits with other research

Klusek et al. (2015) later pooled nine similar baby projects, including this one, and found small social gains plus happy parents. The review treats Green et al. (2013) as a building block, not proof.

Klein et al. (2024) kept the parent-coach idea but moved it online in India. They also saw high parent satisfaction, showing the plan travels to Zoom and new cultures.

Chandler et al. (2002) did an earlier home program, but waited until toddlers were 2–3 years. Starting at 8–10 months is newer and still unproven for changing later diagnosis.

04

Why it matters

If you work with families who already have one autistic child, you can offer this low-stress, video-aided coaching as soon as the new baby arrives. Tell parents it is only a feasibility plan—no promise of prevention yet—and use it while they wait for fuller services.

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Start a 5-minute parent video review during intake for new infant siblings and teach one interaction tip per visit.

02At a glance

Intervention
parent training
Design
case series
Sample size
8
Population
not specified
Finding
not reported

03Original abstract

Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism.

Journal of autism and developmental disorders, 2013 · doi:10.1007/s10803-013-1797-8